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Your Ultimate Guide to Payer Marketing

Discover how payer marketing helps pharma gain market access, optimize pricing, and navigate reimbursement in a value-based healthcare system.
ImageNewristics Image01 Feb 2024
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Payer marketing plays a significant role in shaping the backbone of the pharmaceutical industry. Whether it’s about promoting a pharma product or service, or improving patient access and its coverage, the strategic approach of payer marketing has proved to be indispensable in the evolving landscape of the healthcare sector.  

Who are the payers, and how exactly do they influence the pharma industry? Starting from the insurance companies to the pharmacy benefit managers ( PBMs) and government programs ​like Medicare or Medicaid ​- all of them more popularly known as payers - have a significant influence on determining drug access, and reimbursement.

Effective engagement with the payers is crucial to ensuring drug reimbursement, enhancing market access, and keeping up with the profitability.  

The healthcare industry has seen a massive shift towards value-based care, where​ decision making is predominantly driven by cost containment, and patient outcomes.  

The Key Trends of The Current Healthcare Landscape At A Glance 

Rise of Value-Based Care

Today, drug sales are not the sole priority. At present, the focus has shifted to health outcomes, and the payers’ demand for evidence-based drug’s effectiveness is on the rise. 

Stricter Cost Containment Measures

With both ​government and private insurers implementing stricter cost control policies, gaining market access has become more challenging than ever. Policies like Medicare price negotiations under the Inflation Reduction Act and rigorous formulary management by private payers are driving tighter reimbursement standards and increased pressure on drug pricing. 

Decision making is now data driven

Artificial Intelligence (AI) and real-world evidence (RWE) are now taking the center stage. These encourage the payers to justify pricing and reimbursement with stronger data.  

The Challenges for Pharma Marketers 

#1

Exhibiting long-term values to the payers has become difficult.

#2

Decoding the complex and always changing regulatory requirements.

#3

Dealing with the obstacles to market access and reimbursement.

In this blog, we will guide you through payer marketing essentials, challenges, effective strategies, and emerging trends, ​sharing ​useful and efficient solutions in payer marketing.

Decoding the Role of Payers and Their Impact on the Pharma Sector 

Who Are Payers? 

Payers in the pharma industry can be categorized into two: 

Private Payers

These include the ​i​nsurance companies and PBMs that negotiate drug prices and reimbursement rates. 

Employer-Sponsored Plans

These cover health expense coverage as offered by the employers. 

Here’s How Payers Influence Pharma 

Payers directly influence certain important aspects of the pharmaceutical industry. Like:

Formulary Decisions

They identify which drugs would get covered under health plans. 

Reimbursement Models

The extent of coverage and how much would the patients’ out-of-pocket costs be decided by the payers.  

Patient Access

Whether or not the patient gets access to insurance claims lies in the hands of the payers. They approve or restrict access to specific treatments based on cost and effectiveness. 

Key Payer Priorities 

Cost-Effectiveness

Preference for affordable yet effective treatments. 

Clinical Outcomes

Drugs must demonstrate real-world effectiveness. 

Budget Impact

Payers assess the financial impact of covering a drug on their healthcare budget. 

Challenges in Payer Marketing and How to Overcome Them 

#1

Market Access Hurdles 

Challenge: Market entry gets difficult, thanks to the regulatory measures, and competitive pricing.  

Solution: The journey becomes smoother when there is early engagement with payers with strong clinical and economic proofs.

Pfizer faced declining sales post-COVID, particularly with their migraine drug Nurtec, due to insurance hurdles and ineffective sales strategies. They ​​revamped their approach​ by creating a phone line for doctors and patients to navigate insurance, and by reallocating sales reps to key regions and emphasizing in-person doctor meetings. These changes resulted in a 31% increase in Nurtec's US sales in 2024.

#2

Demonstrating Long-Term Value 

Challenge: Payers look for evidence for long-term merits before giving approvals to reimbursement. 

Solution: Use health economics and outcomes research (HEOR) to showcase cost savings and patient benefits. 

Novartis entered into ​value-based pricing agreements​ with Aetna and Cigna for its heart failure drug, Entresto​, linking reimbursement to the drug's performance in reducing hospitalizations and mortality rates​. 

#3

Adapting to an Evolving Regulatory Environment

Challenge: The US ​m​arket is known for frequent policy changes, which affect pricing and reimbursement models. 

Solution: Stay updated on regulatory trends and engage with policymakers proactively.  

Johnson & Johnson announced plans to invest over $55 billion in building new manufacturing plants in the United States over the next four years. This strategic move aligns with President Trump's push for reshoring drug production and responds to potential tariffs on imported pharmaceuticals. By investing domestically, J&J aims to bolster its American operations and navigate the evolving regulatory landscape effectively. 

Top Strategies for Efficient Payer Marketing 

Value-Based Messaging 

​Pharmaceutical companies are increasingly adopting messaging approaches  highlighting their value-based pricing strategies to align drug prices with the clinical benefits they provide. This approach ensures that the cost of a medication reflects its effectiveness in improving patient outcomes and reducing overall healthcare expenses.  

Real-World Evidence (RWE) and Health Economics and Outcomes Research (HEOR) 

Pharmaceutical companies leverage RWE and HEOR to demonstrate the real-world effectiveness of drugs, helping secure payer approvals by showcasing cost-effectiveness and patient outcomes. 

Pfizer and Bristol Myers Squibb used RWE to support the value of Eliquis (apixaban), a blood thinner used for stroke prevention in patients with atrial fibrillation. Data from insurance claims and electronic health records demonstrated its lower risk of bleeding compared to warfarin, influencing coverage decisions by insurers and Medicare. 

Early Payer Engagement and Collaboration 

Early collaboration with payers ensures new therapies meet reimbursement criteria and align with insurer expectations, facilitating smoother market 

Novartis engaged early with payers before launching Zolgensma, a $2.1 million gene therapy for spinal muscular atrophy (SMA). The company worked with insurers like Aetna and Cigna to develop outcomes-based payment models, ensuring affordability and long-term access to the treatment. 

Risk-Sharing and Innovative Contracting Models 

Risk-sharing agreements help balance financial risks between pharma companies and insurers, improving patient access to high-cost treatments. 

Merck introduced an outcomes-based contract with Express Scripts for Januvia, a diabetes drug. The agreement linked reimbursement to the drug’s ability to help patients achieve specific blood sugar control targets, reducing the financial burden on insurers and ensuring value-based pricing. 

Digital Transformation in Payer Engagement 

​​P​harma companies are adopting digital tools to enhance payer engagement, using data analytics, AI, and telehealth solutions to optimize communication and reimbursement negotiations. 

GlaxoSmithKline (GSK) launched an AI-driven payer engagement platform to provide real-time insights on Trelegy Ellipta, a triple therapy for COPD. The system used predictive analytics to tailor value messaging for payers, improving formulary placement and negotiation outcomes. 

Best 2025 Trends Redefining Payer Marketing 

#1

Personalized Medicine and Specialty Drugs: A New Era of Reimbursement 

The rise of personalized medicine—where treatments are tailored to an individual's genetic makeup—has significantly disrupted traditional reimbursement models. Payers are now forced to adapt, balancing high-cost therapies with long-term clinical benefits. 

Blue Cross Blue Shield has been actively working with Novartis on outcomes-based reimbursement for Kymriah, a CAR-T cell therapy for leukemia that costs over $475,000 per dose. The insurer only pays if the patient responds positively within a specified time, ensuring both financial sustainability and patient success. 

#2

AI and Machine Learning in Decision-Making: The Smart Way to Optimize Payer Strategies 

Artificial Intelligence (AI) and Machine Learning (ML) are transforming payer marketing by predicting drug value, improving formulary placement strategies, and identifying high-risk patient populations. 

UnitedHealth Group’s Optum uses AI-driven analytics to assess the real-world effectiveness of medications. By analyzing vast amounts of claims data, Optum predicts how specific drugs perform across different patient demographics, helping payers refine prior authorization requirements and ensure the most cost-effective drugs are covered first. 

#3

Growth in Value-Based Agreements: Shifting the Focus to Patient Outcomes 

Traditional fee-for-service models are being replaced with value-based agreements, where reimbursement is tied to real-world patient outcomes rather than just drug sales. This shift incentivizes pharmaceutical companies to prove their therapies work in real-life scenarios. 

Eli Lilly’s value-based contract for Trulicity (a diabetes drug) with Harvard Pilgrim Health Care tied reimbursement to patients' improving their HbA1c levels within a set timeframe, ensuring the drug delivered actual clinical benefits. 

#4

Real-Time Market Access Optimization: The Power of Data and Early Engagement 

In today’s competitive landscape, the key to faster drug approvals and favorable reimbursement lies in leveraging big data analytics to: 

  • Identify payer preferences early in drug development.
  • Understand competitive landscapes to anticipate potential hurdles.
  • Build strong relationships with payers before market entry.

​​Pfizer used big data analytics and payer engagement tools while launching Ibrance, its blockbuster breast cancer drug. By analyzing historical claims data, Pfizer anticipated coverage concerns and engaged major payers like Cigna and United Healthcare with tailored pricing strategies, ensuring rapid formulary inclusion.

Pharma companies should start engaging payers during Phase II or III trials, leveraging real-world data to build a strong case for reimbursement before launch. 

Conclusion

Stay updated on regulatory trends and engage with policymakers proactively. 
Johnson & Johnson announced plans to invest over $55 billion in building new manufacturing plants in the United States over the next four years. This strategic move aligns with President Trump's push for reshoring drug production and responds to potential tariffs on imported pharmaceuticals. By investing domestically, J&J aims to bolster its American operations and navigate the evolving regulatory landscape effectively. 

Key Takeaways 

  • Payers control market access and reimbursement. 
  • Marketing strategies and messaging should prioritize demonstrating cost-effectiveness and clinical outcomes. 
  • Market access hurdles can be overcome with early collaboration and strong data. 
  • AI and big data are shaping the future of payer marketing. 
  • Value-based agreements and real-world evidence are critical for securing reimbursement.